Józef Polikarp Brudziński (26 January 1874, Bolewo – 18 December 1917) was a Polish pediatrician who was born in the village of Bolewo (now in Mława County).
He studied medicine in Tartu and Moscow, and in 1897 moved to Krakow, where he trained in pediatrics. Later he worked in Graz under Theodor Escherich (1867-1911), and in Paris with Doctors Jacques-Joseph Grancher (1843-1907), Antoine Marfan (1858-1942 ) and Victor Henri Hutinel (1849-1933).
In 1903 he practiced medicine at the Anne-Marie Kinderhospital in Łódź, and in 1910 moved to Warsaw where he designed a children's hospital with financial assistance from philanthropist Sophie Szlenker. He was a catalyst in the re-establishment of a Polish university in Warsaw, where in 1915 he became rector. In 1908 he founded the first Polish journal of pediatrics, titled Przegląd Pedyatryczny.
Brudziński is remembered for his work involving prophylaxis of infectious diseases in children, and the study of neurological signs associated with meningitis. Today his name is lent to four eponymous medical signs associated with reflexes observed in meningitis.